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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR4 All Species: 9.39
Human Site: S791 Identified Species: 18.79
UniProt: P22455 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22455 NP_002002.3 802 87954 S791 H D P L P L G S S S F P F G S
Chimpanzee Pan troglodytes XP_518127 807 88293 S796 H D P L P L G S S S F P F G S
Rhesus Macaque Macaca mulatta XP_001087243 802 87975 S791 H D P L P L G S S S F P F G S
Dog Lupus familis XP_546211 858 94257 P848 H D L L P L G P S S F S F P G
Cat Felis silvestris
Mouse Mus musculus Q03142 799 88643 P788 H D P L P L E P S P F P F S D
Rat Rattus norvegicus Q498D6 800 88690 P789 H D P L P L E P S P F P F P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P18460 806 89712 E791 A H D L L P D E P C L P K H V
Frog Xenopus laevis Q91743 828 93399 S813 A P D P V P S S P C V F N Y H
Zebra Danio Brachydanio rerio Q90413 922 103447 E902 T H D A L S T E P C L L G Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 E719 T S D E E E D E T D N L Q K W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10656 1040 118938 N1006 V E P P N D P N H L Y C N D N
Sea Urchin Strong. purpuratus Q26614 972 110463 V961 S P Q V Y Y K V P Q T R D C C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 97.3 86.7 N.A. 89.7 88.7 N.A. N.A. 61.5 63.8 56.4 N.A. 35.5 N.A. 30.9 34.2
Protein Similarity: 100 89.7 98.3 88.5 N.A. 92.5 91.6 N.A. N.A. 72.9 74.6 68.6 N.A. 52.1 N.A. 46.1 49.2
P-Site Identity: 100 100 100 66.6 N.A. 66.6 66.6 N.A. N.A. 13.3 6.6 0 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 100 100 66.6 N.A. 66.6 66.6 N.A. N.A. 13.3 6.6 0 N.A. 6.6 N.A. 33.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 25 0 9 0 9 9 % C
% Asp: 0 50 34 0 0 9 17 0 0 9 0 0 9 9 9 % D
% Glu: 0 9 0 9 9 9 17 25 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 50 9 50 0 0 % F
% Gly: 0 0 0 0 0 0 34 0 0 0 0 0 9 25 9 % G
% His: 50 17 0 0 0 0 0 0 9 0 0 0 0 9 17 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 9 9 0 % K
% Leu: 0 0 9 59 17 50 0 0 0 9 17 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 9 0 0 9 0 17 0 9 % N
% Pro: 0 17 50 17 50 17 9 25 34 17 0 50 0 17 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 9 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 9 9 0 0 0 9 9 34 50 34 0 9 0 9 25 % S
% Thr: 17 0 0 0 0 0 9 0 9 0 9 0 0 0 0 % T
% Val: 9 0 0 9 9 0 0 9 0 0 9 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 9 9 0 0 0 0 9 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _